Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10157748 | Pathology - Research and Practice | 2018 | 20 Pages |
Abstract
LIN28 is a very specific marker (98% specificity) for distinguishing classic GHCs from HCCs though it is not as sensitive as SALL4. AFP, glypican-3, Hep Par1 and p-CEA are not useful in distinguishing classic GHCs from HCCs. Combining LIN28 and SALL4 increased the sensitivity to distinguish classic PHCs from HCCs.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Ming Zhao, Lu Sun, Jenny Z. Lai, Huaiyin Shi, Kaiyong Mei, Xianglei He, Xiaolong Jin, Jinping Lai, Dengfeng Cao,