Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10158584 | Toxicology and Applied Pharmacology | 2018 | 8 Pages |
Abstract
Our findings suggest that increased prostanoid production and hypersensitivity to thromboxane A2 together with down-regulation of potassium channels and low nitric oxide bioavailability may contribute to the increase in blood pressure found in adult MSG-obese male rats.
Keywords
KATPATP-dependent K+ channelsEDCFpD2EDHFU46619EmaxA23187TxA2cGMPCOXMSGBKCal-NAMENω-nitro-l-arginine methyl esterROScyclooxygenasemaximal effectThromboxane A2Metabolic syndromeObesitycyclic guanosine monophosphatesodium nitroprussideNitric oxideprostaglandinSNPPotassium channelsmonosodium glutamateReactive oxygen speciescalcium ionophore
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Authors
MichaÅ Majewski, Adam JurgoÅski, Bartosz Fotschki, Jerzy JuÅkiewicz,