Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10158608 | Chemico-Biological Interactions | 2018 | 9 Pages |
Abstract
Although the results cannot be directly extrapolated to the human situation, pharmacokinetics and the effects over time related to plasma levels of therapeutics in a freely moving guinea pig could aid translational models and possibly improve prediction of efficacy in humans.
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Authors
Marloes J.A. Joosen, Steven D. Klaassen, Elwin Verheij, Tomas van Groningen, Alex S. Cornelissen, Mario H. Skiadopoulos, Laura Cochrane, Jeff D. Shearer,