Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10158614 | Chemico-Biological Interactions | 2018 | 33 Pages |
Abstract
All of our results revealed the epigenetic silencing of SFRP5 by promoter methylation plays pivotal roles in chondrosarcoma development and metastasis through SFRP5/Wnt/β-catenin signaling axis. Modulation of their levels may serve as potential targets and diagnostic tools for novel therapeutic strategies of chondrosarcoma.
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Authors
Wei Sheng, Zhi-Cai Zhang, De-Yao Shi, Bai-Chuan Wang, Qiang Wu, Zeng-Wu Shao, Shu-Hua Yang, Tong-Chuan He, Jian-Xiang Liu,