Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10168252 | Diagnostic Microbiology and Infectious Disease | 2016 | 5 Pages |
Abstract
The 2014-2015 influenza season in Belgium was dominated by the circulation of 2 influenza A(H3N2) subgroups: 3C.2a and 3C.3b. Analysis of 166 nasopharyngeal aspirates, collected in patients with respiratory illness at the start of the epidemic season, showed a decreased sensitivity for the detection of influenza A(H3N2)/3C.2a using a commercially available multiplex assay. Gene sequencing of the matrix protein showed a point mutation (C163T) leading to a mismatch with the assay probes.
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Authors
Yarah Overmeire, Elke Vanlaere, Anneleen Hombrouck, Hans De Beenhouwer, Guus Simons, Antoinette Brink, Anne-Marie Van den Abeele, Charlotte Verfaillie, Jos Van Acker,