Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10174895 | Journal of Orthopaedic Science | 2016 | 7 Pages |
Abstract
Clinical and basic research has been performed to determine the pathogenesis of steroid-induced ONFH. Low hepatic CYP3A activity has been reported to significantly contribute to the risk of steroid-induced ONFH. Several gene polymorphisms related to steroid metabolism were shown to be associated with the occurrence of ONFH.
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Authors
Toshikazu Kubo, Keiichiro Ueshima, Masazumi Saito, Masashi Ishida, Yuji Arai, Hiroyoshi Fujiwara,