Article ID Journal Published Year Pages File Type
10175197 Journal of Orthopaedic Science 2012 5 Pages PDF
Abstract
Multiple epiphyseal dysplasia (MED) is a form of osteochondrodysplasia characterized by abnormal epiphyseal growth and assumed to be a clinical condition of extracellular matrix abnormality [1]. Osteoarthritis and chondral lesions, for example osteochondritis dissecans (OCD), are among the clinical expressions of MED [2, 3]. It is possible for osteoarthritic changes of the knee to develop easily even in young patients with MED [4]. Total knee arthroplasty (TKA) and correction osteotomy have been performed for severe deformity and destruction of the knee in MED patient [4, 5].
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