| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10175575 | Journal of Orthopaedic Science | 2010 | 7 Pages |
Abstract
Half of the DRG neurons innervating the discs were positive for CGRP in the puncture + saline group. CGRP is important for mediating inflammatory and nerve-injured pain and may be important in discogenic pain. However, p75NTR saporin suppressed CGRP expression in DRG neurons. Therefore, p75NTR may be an important receptor for mediating discogenic pain via CGRP expression.
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Authors
Ai Sugiura, Seiji Ohtori, Masaomi Yamashita, Kazuyo Yamauchi, Gen Inoue, Munetaka Suzuki, Masaki Norimoto, Sumihisa Orita, Yawara Eguchi, Kazuki Kuniyoshi, Nobuyasu Ochiai, Shunji Kishida, Masashi Takaso, Yasuchika Aoki, Tetsuhiro Ishikawa, Gen Arai,