Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10211546 | Journal of Stroke and Cerebrovascular Diseases | 2018 | 4 Pages |
Abstract
An 85-year-old woman diagnosed with amyotrophic lateral sclerosis died of pneumonia and was autopsied. Magnetic resonance imaging (MRI) performed 16 days before death revealed an intracortical high-intensity lesion in her right temporal cortex on three-dimensional (3D)-double inversion recovery (DIR) and 3D-fluid-attenuated inversion recovery (FLAIR) images. Histopathological examination indicated a cortical microinfarct (CMI) juxtaposed to cerebral amyloid angiopathy. Recently, in vivo detection of CMIs using 3D-DIR and 3D-FLAIR on 3-tesla MRI has been reported, and postmortem MRI study confirmed the presence of CMIs. This is the first case study to compare CMI findings detected upon premortem MRI to the CMI itself discovered upon postmortem neuropathological examination.
Keywords
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Authors
Hidehiro MD, Yuichiro MD, PhD, Atsushi MD, PhD, Akihiro MD, PhD, Ai MD, Keita MD, Ryogen MD, PhD, Kenichiro MD, Masayuki MD, PhD, Hidekazu MD, PhD,