| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10212278 | Frontiers in Neuroendocrinology | 2018 | 91 Pages |
Abstract
Certain mood disorders and autoimmune diseases are predominately female diseases but we do not know why. Here, we explore the relationship between depression and the immune system from a sex-based perspective. This review characterizes sex differences in the immune system in health and disease. We explore the contribution of gonadal and stress hormones to immune function at the cellular and molecular level in the brain and body. We propose hormonal and genetic sex specific immune mechanisms that may contribute to the etiology of mood disorders.
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Authors
Jennifer R. Rainville, Mariya Tsyglakova, Georgia E. Hodes,