Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10216932 | Journal of Dermatological Science | 2018 | 10 Pages |
Abstract
We successfully established iPSC-derived MSCs from keratinocytes (KC-iPSC-MSCs) of a normal human and an RDEB patient. KC-iPSC-MSCs may have potential in therapies for RDEB.
Keywords
MEFLPEMSCDAPIFABP4BMP4BM-MSCsIPSCbFGFα-MEM6-bromoindirubin-3′-oximeRDEBFITCMACSFBSMesenchymal stem/stromal cellFACSNHEKEGF4′,6-diamidino-2-phenylindoleC57BL/6C57BL/6 mouseMOINOD/SCIDhuman leucocyte antigenHLAdermal-epidermal junctionBIOIntravenous injectionSubcutaneous injectionAlpha minimum essential mediumfluorescence-activated cell sortingDEJfetal bovine serumInduced pluripotent stem cellConditioned mediumepidermal growth factorbasic fibroblast growth factorphycoerythrinfluorescein isothiocyanateMHCmajor histocompatibility complexmagnetic-activated cell sortingmouse embryonic fibroblastfatty acid binding protein 4bone morphogenetic protein 4multiplicities of infectionNormal human epidermal keratinocyterecessive dystrophic epidermolysis bullosaepidermolysis bullosa
Related Topics
Health Sciences
Medicine and Dentistry
Dermatology
Authors
Chihiro Nakayama, Yasuyuki Fujita, Wakana Matsumura, Inkin Ujiie, Shota Takashima, Satoru Shinkuma, Toshifumi Nomura, Riichiro Abe, Hiroshi Shimizu,