Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10220250 | Gynecologic Oncology | 2018 | 6 Pages |
Abstract
Many high-risk women do not receive GCR despite a high rate of germline mutations among these women. Improving GCR among high-risk women will lead to more subsequent GT to identify more Lynch syndrome families and prevent additional cancers. Among our ethnically diverse cohort, two women diagnosed with LS had retained MMR protein expression. GCR should be offered to women who possess high-risk characteristics despite normal MMR protein expression.
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Authors
Jessica Lee, Lindsay R. Gubernick, Allison L. Brodsky, Julia E. Fehniger, Douglas A. Levine, Deanna Gerber, Shabnam A. Asgari, Anna Cantor, Jessica T. Martineau, Ophira M. Ginsburg, Julia A. Smith, Bhavana Pothuri,