Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10221810 | European Annals of Otorhinolaryngology, Head and Neck Diseases | 2018 | 7 Pages |
Abstract
The controversy in the RCTs about the superiority of medical treatment over placebo in LPR disease is probably due to discrepancies in the diagnosis method, exclusion criteria, therapeutic schemes and the lack of comprehensive tools for the assessment of signs and symptoms. In this context, the LPR Study Group of Young-Otolaryngologists of the International Federations of Oto-Rhino-Laryngological Societies developed two new instruments to precisely assess signs and symptoms throughout the treatment. These two instruments could be used in future trials comparing medical treatment over placebo in LPR disease.
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Authors
J.R. Lechien, A. Schindler, A.L. Hamdan, F. Bobin, M.R. Barillari, B. Harmegnies, D. Dequanter, A. Rodriguez, E. Bartaire, T. Ayad, P. Karkos, L. Crevier-Buchman, C. Finck, S. Saussez,