| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10222307 | Biological Psychiatry | 2018 | 34 Pages |
Abstract
Our data identified a novel AMPAR activation-independent mechanism underlying the antidepressant effects of (S)-norketamine. (S)-Norketamine and its prodrugs could be novel antidepressants without the detrimental side effects of (S)-ketamine.
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Authors
Chun Yang, Shizuka Kobayashi, Kazuhito Nakao, Chao Dong, Mei Han, Youge Qu, Qian Ren, Ji-chun Zhang, Min Ma, Hidetoh Toki, Jun-ichi Yamaguchi, Shigeyuki Chaki, Yukihiko Shirayama, Kazu Nakazawa, Toshiya Manabe, Kenji Hashimoto,