| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10222848 | Surgery | 2018 | 8 Pages |
Abstract
miR-106a was downregulated in trauma patients after major injury for up to 48 hours after intensive care unit admission. Tumor necrosis factor α and interleukin-10 are targeted by miR-106a, which are regulators of the immune response. Manipulation of micro-RNA expression may be a therapeutic target for immune dysfunction.
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Authors
Norman J. MBChB PhD MRCS, Stephen J. MB BCh, Samuel P. BS, Sarah A. BS, Hiram C. MD, Stephen L. MD,