Article ID Journal Published Year Pages File Type
10224693 British Journal of Anaesthesia 2018 9 Pages PDF
Abstract
RYR1 pG2435R mice demonstrated gene dose-dependent in vitro and in vivo responses to pharmacological and environmental stressors that parallel those seen in patients with the human RYR1 variant p.G2434R.
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Related Topics
Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Preview
Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1
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