Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10227118 | Parkinsonism & Related Disorders | 2018 | 22 Pages |
Abstract
This study revealed that approximately three out of four post-mortem DBS cases exhibited pathological evidence of a glial collar or scar present at the ventral DBS lead tip. The amount of gliosis was not significantly associated with duration of DBS. Future studies should include serial sectioning across all DBS contacts with correlation to the volume of tissue activation and to the clinical outcome.
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Authors
Vinata Vedam-Mai, Cooper Rodgers, Ashley Gureck, Michael Vincent, Gianna Ippolito, Ahmad Elkouzi, Anthony T. Yachnis, Kelly D. Foote, Michael S. Okun,