| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10246959 | Journal of Molecular Catalysis A: Chemical | 2005 | 9 Pages |
Abstract
Oxidation of praziquantel by iodosylbenzene using iron(III) tetraarylporphyrins and manganese(III) tetraphenylporphyrin as catalysts was studied. The majority of the oxidation products have been identified by sequential LC-MS/MS and NMR analyses. The selectivities of the oxidations by these cytochrome P-450 models are studied and compared. The initial oxidation occurs predominantly at the 7-position.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Andrea J.B. Melo, Yassuko Iamamoto, Ana Paula J. Maestrin, John R. Lindsay Smith, Michel D. Santos, Norberto P. Lopes, Pierina S. Bonato,