| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10252658 | Forensic Science International | 2005 | 8 Pages |
Abstract
A simple procedure based on a common silica gel column chromatography for the isolation of Î9-tetrahydrocannabinolic acid A (Î9-THCA-A) from hemp in a multi-milligram scale is presented. Further, the decarboxylation reaction of Î9-THCA-A to the toxicologically active Î9-tetrahydrocannabinol (Î9-THC) at different analytical and under-smoking conditions is investigated. Maximal conversion in an optimised analytical equipment yields about 70% Î9-THC. In the simulation of the smoking process, only about 30 % of the spiked substance could be recovered as Î9-THC.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Franz E. Dussy, Cornelia Hamberg, Marco Luginbühl, Thomas Schwerzmann, Thomas A. Briellmann,