Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10255262 | Pathology | 2005 | 13 Pages |
Abstract
It is possible, as further data accumulate concerning the importance of integration of high-risk HPV DNA into the host cell genome and the reliability with which this can be identified by p16INK4a immunostaining, that this will become the diagnostic 'lesion of interest', replacing the subjective histological grading of cervical dysplasia, in the management of such patients; i.e., the discriminatory watershed between continued surveillance and active intervention.
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Authors
Michael Dray, Peter Russell, Chris Dalrymple, Neil Wallman, george Angus, Adelyn Leong, Jonathan Carter, Bharathi Cheerala,