Enteric coating process of diclofenac sodium pellets in a fluid bed coater with a wurster insert: Influence of process variables on coating performance and release profile

► Temperature and suspension flow rate affected efficiency and agglomeration index. ► Higher suspension flow rates resulted in better coating efficiencies. ► Higher temperatures and suspension flow rates provided more agglomeration. ► To achieve the enteric release, a mass gain of 9.7% was necessary. ► Neither the drug content nor the release profiles were affected by stability test.