Correlation of the mean ionic activity coefficients of electrolytes in aqueous amino acid and peptide systems

The activity coefficients of electrolytes in amino acid (peptide) aqueous systems were predicted using an expression for the excess Gibbs free energy of the solution. The model combines the contribution of long-range interactions given by the Khoshkbarchi-Vera model and the contribution of short-range interactions by the local composition based models such as the Wilson, the NRTL and the NRTL-NRF. The local composition models accurately correlate the activity coefficients of 30 amino acid (peptide)-water-electrolyte systems. The results show that the Wilson model can accurately correlate the activity coefficient of the electrolyte in amino acid (peptide) aqueous systems.