| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10280833 | Powder Technology | 2011 | 7 Pages |
Abstract
⺠Study the effect of concentration and type of insoluble diluents on the release profile of tablets containing HPMC matrices. ⺠Study the compression behavior of the tablets containing insoluble diluents namely MCC and DCP using Heckel and Kawakita equations. ⺠Investigate the effect of compression forces on the release. ⺠Increase in concentration of insoluble diluent causes decrease in the drug release. ⺠During compression MCC shows good plastic deformation, densification and granule fragmentation pattern than DCP an also there is decrease in drug release as we increase the compression force.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
M.P. Vaidya, A.M. Avachat,