| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10298628 | European Neuropsychopharmacology | 2015 | 21 Pages |
Abstract
The present pilot data suggests NPSR1 gene variation to modulate Glx levels in the ACC during acute states of stress and anxiety, with blunted, i.e. possibly maladaptive ACC glutamatergic reactivity in T risk allele carriers. Our results underline the notion of a genetically driven rapid and dynamic response mechanism in the neural regulation of human anxiety and further strengthen the emerging role of the NPS system in anxiety.
Keywords
Related Topics
Life Sciences
Neuroscience
Biological Psychiatry
Authors
Tillmann Ruland, Katharina Domschke, Valerie Schütte, Maxim Zavorotnyy, Harald Kugel, Swantje Notzon, Nadja Vennewald, Patricia Ohrmann, Volker Arolt, Bettina Pfleiderer, Peter Zwanzger,