Article ID Journal Published Year Pages File Type
10301501 Hormones and Behavior 2011 8 Pages PDF
Abstract
► Orexin neurons in the lateral hypothalamic area and perifornical-dorsomedial hypothalamus are activated by cues predictive of sexual reward. ► Cell body specific lesions of orexin neurons block mating-induced conditioned place preference, but do not block conditioned place aversion to lithium chloride induced visceral illness or sexual performance. ► These findings suggest that orexin is critical for reward processing and specifically for conditioned cue induced seeking of sexual reward.
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