| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10304148 | Psychiatry Research | 2015 | 4 Pages |
Abstract
Six single nucleotide polymorphisms (SNPs) of the KCNK2 gene were investigated for their association with major depressive disorder (MDD) and treatment efficacy in 590 MDD patients and 441 controls. The A homozygotes of rs10779646 were significantly more frequent in patients than controls whereas G allele of rs7549184 was associated with the presence of psychotic symptoms and the severity of disease. Evaluating the Sequenced Treatment Alternatives to Relieve Depression (STARâD) dataset, we confirmed our findings.
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Authors
Chiara Congiu, Alessandra Minelli, Cristian Bonvicini, Marco Bortolomasi, Riccardo Sartori, Carlo Maj, Catia Scassellati, Giuseppe Maina, Luigi Trabucchi, Matilde Segala, Massimo Gennarelli,