Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10306009 | Psychoneuroendocrinology | 2008 | 15 Pages |
Abstract
Overall, there were 93% more significant changes in TRH and TRH-like peptide levels in brain and 111% more in peripheral tissues of those rats ingesting various doses of CORT in drinking water compared to those with 1-3 s.c. pellets. We conclude that providing rats with CORT in drinking water is a convenient model for the pathophysiological effects of hyperglucocorticoidemia in rodents.
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Authors
Albert Eugene Pekary, Albert Sattin, James Blood, Stephanie Furst,