| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10306147 | Psychoneuroendocrinology | 2005 | 10 Pages |
Abstract
The aim of these analyses was to develop and describe easily implementable, yet information rich, approaches for analysis of the temporal profile of cortisol in human populations. A typical waking profile of cortisol in a sample of women aged 15-44 was parameterized by a piecewise linear regression model, implemented as a mixed model to accommodate repeated observations among individuals. The model was extended to distinguish characteristic cortisol profiles of obese women from those of non-obese women. Sharp inflection points for the diurnal profile of cortisol were noted at 30 and 75Â min past awakening. Obese women showed a slight tendency to have a less sharply rising and declining response to awakening than non-obese women.
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Authors
Nalini Ranjit, Elizabeth A. Young, Trivellore E. Raghunathan, George A. Kaplan,