| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10306887 | Psychoneuroendocrinology | 2012 | 7 Pages |
Abstract
Our results suggest that biologically active, acetylated ghrelin is involved in reward-associated craving during alcohol withdrawal and early abstinence in alcohol-dependent patients. Antagonizing ghrelin at its central growth-hormone secretagogue receptors (GHS-R1A) in the ventral tegmental area (VTA) may prove to be a novel pharmacological target in a future treatment for craving and relapse in alcoholics.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Anne Koopmann, Christoph von der Goltz, Martin Grosshans, Christina Dinter, Meike Vitale, Klaus Wiedemann, Falk Kiefer,