| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10307406 | Psychoneuroendocrinology | 2019 | 32 Pages |
Abstract
Leptin and acylated ghrelin show opposing effects on mesolimbic cue-reactivity and alcohol craving. We suspect that the reduced striatal cue-reactivity might be the neurobiological correlate of leptin's effect on relapse-risk. The reported results further support the relevance of appetite regulating hormones in the pathophysiology of addiction and their potential role as future treatment targets.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Patrick Bach, Jan Malte Bumb, Rilana Schuster, Sabine Vollstädt-Klein, Iris Reinhard, Marcella Rietschel, Stephanie H. Witt, Klaus Wiedemann, Falk Kiefer, Anne Koopmann,