Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10309788 | Seizure | 2013 | 7 Pages |
Abstract
This retrospective study provided no positive evidence for therapeutic benefits of adding VNS to BDT. The follow-up health status of BDTÂ +Â VNS patients was slightly worse than in patients receiving BDT alone. Despite minor group differences at baseline the two patient groups who had failed presurgical evaluation were comparable. Therapeutic improvements during long-term BDT alone are often underestimated resulting in a misattribution of positive changes to VNS in uncontrolled studies and reviews. Currently, there is no incontrovertible evidence for the clinical effectiveness of adding VNS to BDT.
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Authors
Christian Hoppe, Lena Wagner, Judith M. Hoffmann, Marec von Lehe, Christian E. Elger,