| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10309790 | Seizure | 2013 | 5 Pages |
Abstract
Adult mitochondrial epilepsy appears to be less frequent than previously believed but the prevalence strongly depends on patient selection. Mitochondrial epilepsy is most frequently “structural/metabolic”. AEDs recommended for mitochondrial epilepsy include levetiracetam, lamotrigine, gabapentin and lacosamide. The outcome of mitochondrial epilepsy may be more favourable if mitochondrion-toxic AEDs are avoided. Only if non-mitochondrion-toxic AEDs are ineffective, mitochondrion-toxic AEDs may be used.
Keywords
KSSIOSCACytochrome-c-oxidaseMEMSALBSLMILSNARPMERRFCPEOMdDSSUDEPLHONAEDMELASMIDCOXEPCTCSAHSSDHEMPEncephalopathyMitochondrial disorderEpilepsyseizureTonic–clonic seizureantiepileptic drugantiepileptic drugsCentral nervous system involvementCNSMitochondrial DNA depletion syndromecentral nervous systemepilepsia partialis continuacerebro-spinal fluidCSFsudden unexplained death in epilepsyMiddMIRASEEGLeber's hereditary optic neuropathy
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Authors
Josef Finsterer, Sinda Zarrouk Mahjoub,