Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10317137 | Research in Autism Spectrum Disorders | 2014 | 15 Pages |
Abstract
The objective of this study was to identify a set of 'essential' behaviours sufficient for diagnosis of DSM-5 Autism Spectrum Disorder (ASD). Highly discriminating, 'essential' behaviours were identified from the published DSM-5 algorithm developed for the Diagnostic Interview for Social and Communication Disorders (DISCO). Study 1 identified a reduced item set (48 items) with good predictive validity (as measured using receiver operating characteristic curves) that represented all symptom sub-domains described in the DSM-5 ASD criteria but lacked sensitivity for individuals with higher ability. An adjusted essential item set (54 items; Study 2) had good sensitivity when applied to individuals with higher ability and performance was comparable to the published full DISCO DSM-5 algorithm. Investigation at the item level revealed that the most highly discriminating items predominantly measured social-communication behaviours. This work represents a first attempt to derive a reduced set of behaviours for DSM-5 directly from an existing standardised ASD developmental history interview and has implications for the use of DSM-5 criteria for clinical and research practice.
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Sarah J. Carrington, Rachel G. Kent, Jarymke Maljaars, Ann Le Couteur, Judith Gould, Lorna Wing, Ilse Noens, Ina Van Berckelaer-Onnes, Susan R. Leekam,