Article ID Journal Published Year Pages File Type
10374815 Colloids and Surfaces B: Biointerfaces 2011 5 Pages PDF
Abstract
▶ We have prepared the compound nanoparticles of chitosan and cyclodextrin loading with hydrophilic and hydrophobic drug simultaneously. ▶ Methotrexate and calcium folinate are selected as the mode drugs. ▶ We examine the loading capacity, size, zeta potential and surface morphology of the nanoparticles. ▶ The chitosan/cyclodextrin nanoparticles exhibit stronger sustained release effect comparing to chitosan nanoparticles and the release mechanism followed a non-Fickian type behavior.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
Authors
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