Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10374841 | Colloids and Surfaces B: Biointerfaces | 2011 | 7 Pages |
Abstract
â¶ Discrete, spherical Eudragit S-100 coated chitosan microspheres were successfully prepared. â¶ Microspheres depicted appropriate release patterns in simulated GI fluids. â¶ Enhanced release characteristics in the presence of colonic microflora. â¶ Eudragit S-100 proved to be effective in preventing a premature release of diltiazem in upper GIT. â¶ Chitosan ensured a controlled release of drug in the colon.
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Authors
S. Jose, M.T. Prema, A.J. Chacko, A. Cinu Thomas, E.B. Souto,