Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10374895 | Colloids and Surfaces B: Biointerfaces | 2011 | 8 Pages |
Abstract
⺠Binding interaction of EMPD to HSA is dominated by a static quenching procedure. ⺠Drug-protein complex is stabilized with hydrophobic forces and hydrogen bonding. ⺠The specific binding site of EMPD is located at the subdomains IIA of HSA. ⺠The distance between the donor and the acceptor is estimated as 4.85 nm. ⺠Presence of common metal ions increases the systems binding constants.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Gongke Wang, Dongchao Wang, Xiang Li, Yan Lu,