| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10375018 | Colloids and Surfaces B: Biointerfaces | 2005 | 6 Pages |
Abstract
The interaction of 1-palmitoy-2-oleoyl-sn-glycero-3-phosphocoline (POPC) and 1-palmitoy-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE), two of the major components in biological membranes, were investigated using the monolayer technique at the air-water interface. The pressure-area isotherms indicate that both phospholipids are miscible through all range of compositions. POPE-POPC form stable mixtures, with a minimum for the Gibbs energy of mixing at XPOPCÂ =Â 0.4. A virial equation of state was fitted to the experimental values. Positive values found for the second virial coefficient indicate repulsion between POPC and POPE. The interaction parameter was evaluated which indicated that a corresponding decrease in the repulsion occurs when POPC molar fraction is low. This effect suggests the existence of hydrogen bonds between POPE and the water beneath the interface.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Ãscar Domènech, Juan Torrent-Burgués, Sandra Merino, Fausto Sanz, M. Teresa Montero, Jordi Hernández-Borrell,