Article ID Journal Published Year Pages File Type
10394630 Bioresource Technology 2012 6 Pages PDF
Abstract
► Actinoplanes utahensis ZJB-08196 could grow under moderate hyperosmolality up to 719 mOsm kg−1. ► A successful fed-batch fermentation process for acarbose production was constructed. ► Some components of feed acting as precursor provision and osmoprotection were found. ► This intermittent fed-batch culture produced a peak acarbose titer of 4878 mg l−1.
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Physical Sciences and Engineering Chemical Engineering Process Chemistry and Technology
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Actinoplanes utahensis ZJB-08196 fed-batch fermentation at elevated osmolality for enhancing acarbose production
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