| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10394631 | Bioresource Technology | 2012 | 8 Pages |
Abstract
⺠We have characterized and stabilized a new alcohol dehydrogenase from Thermus thermophillus. ⺠Tt27-ADH2 has the same optimal pH (pH 7) for both reduction and oxidation reactions. ⺠Tt27-ADH2 asymmetrically reduces 2,2â²,2â³-trifluoroacetone with anti-Prelog specificity. ⺠Tt27-ADH2 produces R-profens derivative by asymmetric reduction of aryl-propanal. ⺠Tt27-ADH2 is 200-fold more stable than the soluble enzyme by immobilization.
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Authors
Javier Rocha-MartÃn, Daniel Vega, Juan M. Bolivar, Aurelio Hidalgo, José Berenguer, José M. Guisán, Fernando López-Gallego,