Fabrication of a chitosan/glucose oxidase-poly(anilineboronic acid)-Aunano/Au-plated Au electrode for biosensor and biofuel cell

► Reduction of NaAuCl4 by the hybrid of glucose oxidase and anilineboronic acid yields a polymeric bionanocomposite. ► Small-sized Au (sub) nanostructures can form near/on the enzyme molecule to promote the electron transfer of enzymatic reaction. ► The thus-fabricated enzyme electrode worked very well in the first-/second generation biosensing modes and as a bioanode in a biofuel cell.