Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10429395 | Biosensors and Bioelectronics | 2012 | 6 Pages |
Abstract
⺠A transgenic line of zebrafish had been generated using a CYP-green fluorescence protein (CYP-GFP) construct, driven by CYP1A1 promoter. ⺠After exposed to PCBs, green fluorescence signals in zebrafish liver were found to express according to concentrations and time. ⺠The green fluorescence signal was most intense after treatment with 0.08 μg/ml PCBs. ⺠The maximum area of green fluorescent signal was found at 0.04 μg/ml PCBs. ⺠Transgenic fish with CYP-GFP is a good tool for live imaging and monitoring of aquatic contamination.
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Authors
Karen W.Y. Hung, Miranda F.K. Suen, Y.F. Chen, H.B. Cai, Z.X. Mo, Ken K.L. Yung,