Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10429508 | Biosensors and Bioelectronics | 2011 | 4 Pages |
Abstract
In this study, we propose a novel biosensor based on a gated lateral bipolar junction transistor (BJT) for biomaterial detection. The gated lateral BJT can function as both a BJT and a metal-oxide-semiconductor field-effect transistor (MOSFET) with both the emitter and source, and the collector and drain, coupled. C-reactive protein (CRP), which is an important disease marker in clinical examinations, can be detected using the proposed device. In the MOSFET-BJT hybrid mode, the sensitivity, selectivity, and reproducibility of the gated lateral BJT for biosensors were evaluated in this study. According to the results, in the MOSFET-BJT hybrid mode, the gated lateral BJT shows good selectivity and reproducibility. Changes in the emitter (source) current of the device for CRP antigen detection were approximately 0.65, 0.72, and 0.80 μA/decade at base currents of â50, â30, and â10 μA, respectively. The proposed device has significant application in the detection of certain biomaterials that require a dilution process using a common biosensor, such as a MOSFET-based biosensor.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Heng Yuan, Hyurk-Choon Kwon, Se-Hyuk Yeom, Dae-Hyuk Kwon, Shin-Won Kang,