Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10430236 | Biosensors and Bioelectronics | 2005 | 6 Pages |
Abstract
A GMI-biosensor prototype was designed and fabricated using an amorphous ribbon. As a first step, a GMI response was measured with a model liquid media: suspension containing magnetisable Dynabeads® M-450. These beads can be used as biomolecular labels when coated with a specific antibody. The GMI change caused by their presence was measured with a biosensor prototype designed with a measuring cell containing an amorphous CoFeMoSiB-ribbon element. GMI was measured at a range of current frequencies from 0.3 to 10Â MHz and at intensities of either Irms=3 or 4.5Â mA. Commercial Dynabeads® M-450 were supplied as a suspension in a phosphate buffered saline. A maximum difference of 25% in the GMI ratio measured with and without Dynabeads® was obtained at a frequency of 3.5Â MHz and Irms=3Â mA. Some potential applications for GMI-biosensor and further directions are proposed.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Galina Kurlyandskaya, Vladimir Levit,