Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10432144 | Journal of Biomechanics | 2014 | 4 Pages |
Abstract
Local intracellular variations of cell mechanical properties, which are essential for vital cellular functions, have not been well characterized and are poorly understood. Here, we used results from our previous biomechanical imaging study to obtain relationships between intracellular shear modulus and prestress. We found that the subcellular shear modulus vs. prestress relationships exhibited positive linear correlations, consistent with previously observed behaviors at the whole cell and tissue levels. This, in turn, suggests that the prestress may be a unifying factor that determines material properties of living matter at different length scales.
Related Topics
Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
Elizabeth P. CanoviÄ, D. Thomas Seidl, Paul E. Barbone, Michael L. Smith, Dimitrije StamenoviÄ,