Article ID Journal Published Year Pages File Type
10432624 Journal of Biomechanics 2013 7 Pages PDF
Abstract
In the present study, the electro-mechanical properties of human knee articular cartilage were measured in vitro. An arthroscopic measurement tool was used to measure streaming potential integral (SPI), after which creep indentation tests were performed. Additionally, degradation level of the tissue was determined in accordance with the International Cartilage Repair Society (ICRS score), and hematoxylin/eosin and safranin O staining were performed to determine the Mankin score. Mechanical test results were evaluated both analytically and by means of a finite-element-optimized parameter identification procedure. The SPI was then correlated with poroelastic E modulus (r=0.563, p<0.008, n=22), natural logarithm of hydraulic permeability (r=0.374, p<0.095, n=22) and cartilage degeneration scores (ICRS and Mankin) (r=−0.749, p<0.000, n=22 and r=−0.409, p<0.059, n=22 respectively).
Related Topics
Physical Sciences and Engineering Engineering Biomedical Engineering
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