| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10435366 | Medical Engineering & Physics | 2005 | 13 Pages |
Abstract
This review is designed to introduce the cytoskeleton and then discuss how mechanical forces may be transduced to the cell nucleus. In addition to this, it also tries to explain current thinking as to how the nucleus turns these mechanical cues into gene changes and is especially interested in mechanotransduction arising from topographically induced morphological changes, specifically nanotopography. Thus, this review also describes cell responses to topography.
Related Topics
Physical Sciences and Engineering
Engineering
Biomedical Engineering
Authors
Matthew J. Dalby,