Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10454434 | Biological Psychology | 2008 | 4 Pages |
Abstract
A functional polymorphism (His452Tyr) in the gene encoding the serotonin 2A receptor (HTR2A) has been previously associated with human episodic memory performance and with differences in brain volume in memory-related brain regions. Here we present data obtained through imputation and fine-mapping showing that multiple loci within HTR2A are significantly associated with human memory performance independently of the His452Tyr polymorphism. Our data support the existence of multiple memory-related loci within HTR2A.
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Authors
Jessica C. Sigmund, Christian Vogler, Kim-Dung Huynh, Dominique J.-F. de Quervain, Andreas Papassotiropoulos,