Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10454879 | Brain, Behavior, and Immunity | 2011 | 11 Pages |
Abstract
⺠Intraperitoneal adoptive transfer of peripheral immune cells potentiates chronic constriction injury-induced allodynia. ⺠Peripheral immune cells only capable of potentiating existing allodynia, rather than establishing allodynia. ⺠Intraperitoneal adoptive transfer of high pain splenocytes may induce the migration of host-derived immune cells from the spleen to the CNS. ⺠Intrathecal transfer of “pain-activated” CD45+ cells results in potentiated allodynia.
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Authors
Peter M. Grace, Mark R. Hutchinson, Alan Bishop, Andrew A. Somogyi, Graham Mayrhofer, Paul E. Rolan,