Article ID Journal Published Year Pages File Type
10454879 Brain, Behavior, and Immunity 2011 11 Pages PDF
Abstract
► Intraperitoneal adoptive transfer of peripheral immune cells potentiates chronic constriction injury-induced allodynia. ► Peripheral immune cells only capable of potentiating existing allodynia, rather than establishing allodynia. ► Intraperitoneal adoptive transfer of high pain splenocytes may induce the migration of host-derived immune cells from the spleen to the CNS. ► Intrathecal transfer of “pain-activated” CD45+ cells results in potentiated allodynia.
Related Topics
Life Sciences Immunology and Microbiology Immunology
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