| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10454984 | Brain, Behavior, and Immunity | 2011 | 9 Pages |
Abstract
⺠Continuous stress is shown to disrupt the efficacy of immunostimulation with IL-12. ⺠Both pharmacological and physiological stress paradigms were tested and found deleterious. ⺠The disruption is evident in NK cell number and activity and lung tumor clearance. ⺠The stress hormones corticosterone and epinephrine are potential mediators. ⺠The disruption is more profound in males than in females.
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Authors
Ben Levi, Marganit Benish, Yael Goldfarb, Liat Sorski, Rivka Melamed, Ella Rosenne, Shamgar Ben-Eliyahu,