Article ID Journal Published Year Pages File Type
10454988 Brain, Behavior, and Immunity 2011 10 Pages PDF
Abstract
► Pharmacological depletion of cerebral microglia attenuates waking effects of methamphetamine. ► Methamphetamine upregulates nitric oxide synthase (NOS) activity in microglia. ► Neuronal NOS knockout abolishes microglial NOS activation by methamphetamine. ► Methamphetamine alters sleep regulatory cytokine synthesis in microglia selectively.
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